منابع مشابه
Extra Views Executing Cell Senescence
Senescence is a permanent form of cell cycle arrest that limits the proliferation of damaged cells and may contribute to tumor suppression and aging. We recently demonstrated that some senescent cell types undergo a dramatic changes in chromatin organization that are dependent on the retinoblastoma protein and are associated with the stable repression of some E2F target genes. Here we how these...
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Objective(s): In this paper, we discussed natural agents with protective effects against stem cell senescence. Different complications have been observed due to stem cell senescence and the most important of them is “Aging”. Senescent cells have not normal function and their secretary inflammatory factors induce chronic inflammation in body which causes different patho...
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Low-latency and high-throughput processing are key requirements of data stream management systems (DSMSs). Hence, multi-core processors that provide high aggregate processing capacity are ideal matches for executing costly DSMS operators. The recently developed Cell processor is a good example of a heterogeneous multi-core architecture and provides a powerful platform for executing data stream ...
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senescence has long been established as a stable and irreversible growth arrest, which plays an important role in tumor suppression and tissue repair. It can be induced by various stimuli, including telomere shortening, oncogene activation and oxidative stress. We recently demonstrated that cell-cell fusion is a previously unidentified trigger for inducing cellular senescence [1]. This work was...
متن کاملCell Senescence In Vitro
Cell senescence in vitro refers to the multitude of physiological, structural, biochemical and molecular changes that occur progressively during serial subcultivation of normal diploid cells, culminating in the permanent cessation of cell division. The whole duration of serial passaging is considered as the process of cellular ageing, and the end-stage irreversible growth arrest is termed as re...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2004
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.3.3.699